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Download PDF of article Iron is essential for biochemical functions in the body at every stage of life. The physiological manifestations of iron-deficiency anemia include reduced immune function and resistance to infection, impaired cognitive performance and behaviour, decreased thermoregulatory performance and energy metabolism, diminished exercise or work capacity, and increased incidence of preterm deliveries and low birthweight chxt.

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Iron deficiency anaemia - illnesses & conditions | nhs inform

The comparison with Nutrition Canada data suggests that the prevalence of anemia is currently lower in all age groups younger than While this study found higher rates of anemia cchat seniors, factors other than iron deficiency may have contributed to this result. Similarly, the prevalence of hemoglobin sufficiency was ificantly lower among people in the lowest income quartile, compared with the highest. Six age groups were specified: 3 to 5, 6 to 11, 12 to 19, 20 to 49, 50 to 64, and 65 to 79 years.

Mean serum ferritin wex did not differ ificantly by household income quartile data not shown. For example, vitamin B12 deficiency is a cause of pernicious anemia, with an average age at diagnosis of Concentrations were ificantly higher among males than females.

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A lavender-top EDTA vacutainer of whole blood specimen was collected for the complete blood count analysis. Mean serum ferritin concentrations did not differ ificantly by household income quartile data not shown.

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cat This suggests that the anemia may not have been due to iron deficiency. These adjusted household income values were grouped into approximate quartiles. Although serum ferritin is a valid measure of total iron storage, 9,10 as a sole indicator of iron deficiency, it must be interpreted cautiously; concentrations could increase as a result iiron infections and disorders such as chronic inflammation, malignancy and liver disease.

As well, other evidence indicates adequate dietary iron intake by much of the population.

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Blood collection Blood was collected by venipuncture. This is consistent with other research findings for young women with depleted iron stores, 30,31 though in contrast to those with anemia. Serum vitamin B12 and red blood cell folate analyses were performed on the Immulite The complete blood count analysis included determination of hemoglobin and of mean corpuscular volume.

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Using hemoglobin alone to identify iron deficiency anemia tends to yield overestimates, because anemia due to other causes is included. Household income during the past 12 months was based on the total aex before taxes and deductions of all household members divided by the of people in the household.

Iron range sex chat

The overall response rate was Survey weights produced for the CHMS were used to for the different stages of non-response. Vitamin B12 and red blood cell folate analysis Vitamin B12 and folate deficiency were investigated to determine if factors other than iron deficiency contributed to the prevalence of anemia. The CHMS did not include other iron indices such as soluble transferrin receptor, which could have been helpful in distinguishing iron-deficiency anemia from all-cause anemia.

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Rage A of limitations are associated with this analysis. Hemoglobin concentration alone was used as a measure of anemia. Furthermore, because this is a national sample, regional differences cannot be determinated.

Internal quality control and standardized procedures were developed for every assay performed in this laboratory. As well, other evidence indicates adequate dietary iron intake by much of the population. Table 2 Prevalence of sufficient hemoglobin, by age group and sex, household population aged 3 to 79, Canada, and to A comparison of to CHMS data with of the Nutrition Canada Survey, taking differences in age groups and hemoglobin reference values intosuggests that at most ages, esx percentage of people with hemoglobin concentrations above sfx values has risen during the past 40 years Table 2.

Serum was analysed for ferritin by solid phase, two-site chemiluminescent immunometric assay using the Immulite Siemens HealthCare Diagnostics.

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Red blood cell folate did not appear to contribute to anemia. These data allow for the examination of associations between selected socio-demographic and health variables and measures of iron status. Respondents answered questions about medication use in the past month, including prescriptions, over-the-counter medications, and health irpn and herbal remedies. Hemoglobin concentration alone was used as a measure of anemia. Standardized procedures and quality control monitoring were developed for the collection, processing, aliquoting and analysis of biospecimens and for shipping them to the testing laboratory.

These findings should be interpreted cautiously, as no information was collected about dosage, frequency of use, timing of intake, or reason for taking high-dose supplements.

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The laboratory participates in proficiency testing programs and has strict quality control procedures. Student's t-test was used to test differences between percentages, arithmetic means, and geometric means. A reduction in the size fhat circulating red blood cells, aex as the mean corpuscular volume, is a reliable indication of reduced hemoglobin synthesis; low values can indicate iron-deficient erythropoiesis. These data allow for the examination of associations between selected socio-demographic and health variables and measures of iron status.

Iron deficiency anaemia

No ificant differences in hemoglobin and serum ferritin sufficiency were apparent between those who took iron-containing multivitamins, compared with those who reported no iron supplementation Table 4. Table B World Health Organization hemoglobin, mean corpuscular volume and ferritin reference values for sufficiency, based on criteria, For the most part, the analysis, presents estimates of sufficiency at or above reference valuesbecause this measure yielded larger sample sizes, resulting in a ificant decrease in sampling variability, and thus, more reliable estimates than measures of deficiency below the reference values.

Limitations A of limitations are associated with this analysis.

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Cuat of Indian reserves and Crown lands, institutions and certain remote regions, and full-time members of the Canadian Forces were excluded. This suggests that the anemia may not have been due to iron deficiency. For example, vitamin B12 deficiency is a cause of pernicious anemia, with an average age at diagnosis of Standardized procedures and quality control monitoring were developed for the collection, processing, aliquoting and analysis of biospecimens and for shipping them to the testing laboratory.

Data were collected at 18 sites across Canada from August through November However, this pattern did not persist when serum ferritin was used as a measure of iron stores.